Depending on the case of extraction, membrane proteins can be classified as : 

 Integral and peripheral

The correct answer is Option (3) – Integral and peripheral

The cell membrane is mainly composed of lipids and proteins. The major lipids are phospholipids that are arranged in a bilayer. Also, the lipids are arranged within the membrane with the polar head towards the outer sides and the hydrophobic tails towards the inner part.This ensures that the nonpolar tail of saturated hydrocarbons is protected from the aqueous environment .

In addition to phospholipids membrane also contains cholesterol. Later, biochemical investigation clearly revealed that the cell membranes also possess protein and carbohydrate. The ratio of protein and lipid varies considerably in different cell types. In human beings, the membrane of the erythrocyte has approximately 52 per cent protein and 40 per cent lipids.

Depending on the ease of extraction, membrane proteins can be classified as integral and peripheral. Peripheral proteins lie on the surface of membrane while the integral proteins are partially or totally buried in the membrane.