Match List-I with List-II.
| List-I | List-II |
| 1) Trichoderma polysporum | a) Statins |
| 2) Clostridium butylicum | b) Streptokinase |
| 3) Monascus purpureus | c) Cyclosporin A |
| 4) Streptococcus | d) Butyric acid |
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 1
The correct answer is Option (1) → 1-c, 2-d, 3-a, 4-b
(1) Trichoderma polysporum — this matches (c) Cyclosporin A. This fungus makes cyclosporin A, an immunosuppressive agent given to organ-transplant patients.
(2) Clostridium butylicum — this matches (d) Butyric acid. This bacterium is used for the commercial production of the organic acid butyric acid.
(3) Monascus purpureus — this matches (a) Statins. This yeast makes statins, which lower blood cholesterol.
(4) Streptococcus — this matches (b) Streptokinase. Streptokinase from this bacterium, modified by genetic engineering, is a ‘clot buster’ that removes clots from blood vessels after a heart attack.
NCERT Extract:
Chemicals, Enzymes and Other Bioactive Molecules – “… Examples of acid producers are Aspergillus niger (a fungus) of citric acid, Acetobacter aceti (a bacterium) of acetic acid; Clostridium butylicum (a bacterium) of butyric acid and Lactobacillus (a bacterium) of lactic acid.”
Chemicals, Enzymes and Other Bioactive Molecules – “… Streptokinase produced by the bacterium Streptococcus and modified by genetic engineering is used as a ‘clot buster’ for removing clots from the blood vessels of patients who have undergone myocardial infarction leading to heart attack. Another bioactive molecule, cyclosporin A, that is used as an immunosuppressive agent in organ-transplant patients, is produced by the fungus Trichoderma polysporum. Statins produced by the yeast Monascus purpureus have been commercialised as blood-cholesterol lowering agents.”