Arrange the following steps of retrovirus replication sequentially.
A. Production of viral DNA by reverse transcriptase
B. Introduction of viral RNA in host cell
C. Production of new viral RNA by host cell
D. Incorporation of viral DNA into host genome
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 2
The correct answer is Option (2) → B, A, D, C
Viral RNA enters the host cell (B), reverse transcriptase makes viral DNA (A), the DNA joins the host genome (D), and the host cell makes new viral RNA (C).
Note: A similar question was also asked in CUET (UG) 2023 on 12-06-2023 (Slot 2).
NCERT Extract:
AIDS – “… After getting into the body of the person, the virus enters into macrophages where RNA genome of the virus replicates to form viral DNA with the help of the enzyme reverse transcriptase. This viral DNA gets incorporated into host cell’s DNA and directs the infected cells to produce virus particles (Figure 7.6).”