Practicing Success

Target Exam

CUET

Subject

Biology

Chapter

Human Health and Disease

Question:
Assertion: T-lymphocytes mediate CMI response.
Reasoning:: The above response makes it easy to transplant organs.
Options:
Both Assertion (A) and Reason (R) are correct and R is the correct explanation of A.
Both Assertion (A) and Reason (R) are correct and but R is not the correct explanation of A.
Assertion (A) is true but Reason (R) is not correct.
Both Assertion (A) and Reason are false (F ).
Correct Answer:
Assertion (A) is true but Reason (R) is not correct.
Explanation:
Cell-mediated immunity (CMI) is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic Tlymphocytes, and the release of various cytokines in response to an antigen. The immune response to a transplanted organ consists of both cellular(lymphocyte mediated) and humoral (antibody mediated) mechanisms. Although other cell types are also involved, the T cells are central in the rejection of grafts.