Which one of the following antibodies is mostly responsible for the allergy in patient?
Answer & explanation
Correct answer: option 3
The correct answer is Option (3) → IgE
Allergy is an exaggerated response of the immune system to substances in the environment, such as dust mites, pollen or animal dander. These substances are called allergens. Some of the body’s antibodies are made against them.
(1) IgG — Incorrect. IgG is one of the antibodies that fight infection in the blood. It is not the antibody of allergy.
(2) IgA — Incorrect. IgA is the antibody found in colostrum, the first milk, which protects the infant. It is not the antibody of allergy.
(3) IgE — Correct. The antibodies made against allergens are of the IgE type. They cause the mast cells to release chemicals such as histamine and serotonin. These chemicals produce sneezing, watery eyes, a running nose and difficulty in breathing.
(4) IgM — Incorrect. IgM is another antibody of the blood. It does not cause allergy.
NCERT Extract:
Allergies –
