Out of the given options, the best antonym (opposite) of the word "vicious" is  OPTION 2 - Virtuous
Here's why:

Vicious means deliberately cruel or violent.
Virtuous means morally good and having high moral principles. This directly contrasts the negative connotations of viciousness.
Godly refers to being related to God or a god, which isn't necessarily the opposite of vicious. Someone can be religious and still be cruel.
Sublime refers to something of exceptional beauty or grandeur, which has no connection to the concept of being morally good or bad.
Friendly means showing or feeling kindness, but it doesn't necessarily imply a strong moral character. Someone might be friendly but still capable of cruelty in certain situations.