Match List-I with List-II:

Choose the correct answer from the options given below:

(A)-(III), (B)-(I), (C)-(IV), (D)-(II)

The correct answer is Option (1) → (A)-(III), (B)-(I), (C)-(IV), (D)-(II)

A. The technique of DNA Fingerprinting was initially developed by Alec Jeffreys. He used a satellite DNA as probe that shows very high degree of polymorphism. It was called as Variable Number of Tandem Repeats (VNTR). The technique, as used earlier, involved Southern blot hybridisation using radiolabelled VNTR as a probe.

B. DNA as an acidic substance present in nucleus was first identified by Friedrich Meischer in 1869. He named it as ‘Nuclein’.

C. The elucidation of the lac operon was also a result of a close association between a geneticist, Francois Jacob and a biochemist, Jacque Monod. They were the first to elucidate a transcriptionally regulated system.

D.In 1953, S.L. Miller, an American scientist created a conditions in a laboratory scale . He created electric discharge in a closed flask containing CH₄, H₂, NH₃ and water vapour at 800^oC. He observed formation of amino acids.