Practicing Success

Target Exam

CUET

Subject

Biology

Chapter

Molecular Basis of Inheritance

Question:

Read the passage and answer the following questions :
Translation refers to the process of polymerisation of amino acids to form a polypeptide. The order and sequence of amino acids are defined by the sequence of bases in the mRNA. The amino acids are joined by a bond which is known as a peptide bond. Formation of a peptide bond requires energy.

What binds to the stop codon to terminate translation?

Options:

tRNA

Ribosome

 Release factor

mRNA

Correct Answer:

 Release factor

Explanation:

The correct answer is Otion (3)- Release factor 

For initiation, the ribosome binds to the mRNA at the start codon (AUG) that is recognised only by the initiator tRNA. The ribosome proceeds to the elongation phase of protein synthesis. During this stage, complexes composed of an amino acid linked to tRNA, sequentially bind to the appropriate codon in mRNA by forming complementary base pairs with the tRNA anticodon. The ribosome moves from codon to codon along the mRNA. Amino acids are added one by one, translated into Polypeptide sequences dictated by DNA and represented by mRNA. At the end, a release factor binds to the stop codon, terminating translation and releasing the complete polypeptide from the ribosome.