The correct answer is 1.
DNA-dependent RNA polymerase catalyzes the polymerization of RNA in one direction.Since the two strands have opposite polarity and the DNA-dependent RNA polymerase also catalyse the polymerisation in only one direction. It synthesizes RNA in the 5' to 3' direction using the DNA template strand as a guide. This means that the RNA strand is elongated by adding nucleotides to the 3' end.