Assertion :The first clinical gene therapy was given in 1890 to a 5-year old girl with adenosine deaminase (ADA) deficiency.
Reason : ADA enzyme is crucial for the immune system to function. The disorder is caused due to the deletion of the gene for adenosine deaminase.

Assertion is false but reason is true .

The correct answer is Option (3)- Assertion is false but reason is true .

Gene therapy is a collection of methods that allows correction of a gene defect that has been diagnosed in a child/embryo. Here genes are inserted into a person’s cells and tissues to treat a disease. Correction of a genetic defect involves delivery of a normal gene into the individual or embryo to take over the function of and compensate for the non-functional gene

The first clinical gene therapy was given in 1990 to a 4-year old girl with adenosine deaminase (ADA) deficiency. This enzyme is crucial for the immune system to function. The disorder is caused due to the deletion of the gene for adenosine deaminase. In some children ADA deficiency can be cured by bone marrow transplantation; in others it can be treated by enzyme replacement therapy, in which functional ADA is given to the patient by injection.