Which is the largest known human gene, and how many bases does it have?
Answer & explanation
Correct answer: option 1
The correct answer is Option (1) → Dystrophin; 2.4 million bases
The Human Genome Project (HGP) found the sequence of the whole human genome. One of its findings is that genes differ greatly in size. The largest known human gene is dystrophin, with 2.4 million bases. The figure 3000 bases in Option (2) is the size of an average gene, not of the largest one.
NCERT Extract:
Salient Features of Human Genome – “Some of the salient observations drawn from human genome project are as follows: (i) The human genome contains 3164.7 million bp. (ii) The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases.”