Arrange the following steps of replication of retrovirus in correct sequence.
A. Incorporation of viral DNA into host genome.
B. Formation of viral DNA by reverse transcription.
C. Infection of normal cell by virus and introduction of viral RNA into host
D. Production of new viral RNA by infected cells.
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 3
The correct answer is Option (3) → C → B → A → D
The virus infects a cell and its RNA enters (C); reverse transcription forms viral DNA (B); the DNA is incorporated into the host genome (A); the infected cell then makes new viral RNA (D).
Note: A similar question was also asked in CUET (UG) 2023 on 31-05-2023 (Slot 3).
NCERT Extract:
AIDS – “… After getting into the body of the person, the virus enters into macrophages where RNA genome of the virus replicates to form viral DNA with the help of the enzyme reverse transcriptase. This viral DNA gets incorporated into host cell’s DNA and directs the infected cells to produce virus particles (Figure 7.6).”