The most appropriate synonym of the word "loathe" is abhor.
- Loathe is defined as "to feel intense dislike or disgust for."
- Abhor is defined as "to regard with extreme repugnance or hatred."
- Entrench is defined as "to establish or fix (something) firmly in a position or custom."
- Abjure is defined as "to renounce or reject (something, especially a belief or practice)."
- Meddle is defined as "to interfere in someone else's affairs without being asked."
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