Practicing Success

Target Exam

CUET

Subject

Biology

Chapter

Principles of Inheritance and Variation

Question:

Read the given paragraph and answer the question:

Humans have 23 pairs of chromosomes. 22 pairs are exactly same in both males and females; these are the autosomes. A pair of X-chromosome are present in the female, whereas the presence of an X and Y chromosome are determinant of the male characteristic. A number of disorders in human beings have been found to be associated with the inheritance of changed or altered genes or chromosomes. Broadly, genetic disorder may be grouped into two categories disorders and Chromosomal disorders.

A haemophilic man marries a normal woman. What is the possibility that their child have haemophilia?

Options:

75%

25%

0%

50%

Correct Answer:

0%

Explanation:

The correct answer is Option (3)- 0%

In this scenario, the man is hemophilic, meaning he has the genetic disorder hemophilia, which is typically an X-linked recessive disorder. Hemophilia is caused by mutations in genes that provide instructions for making proteins necessary for blood clotting. Since the gene responsible for hemophilia is located on the X chromosome, it is inherited in an X-linked pattern.

When a hemophilic man (XhY) marries a normal woman (XX), the possible combinations of their offspring are as follows.

Sons: They inherit the Y chromosome from the father and the X chromosome from the mother. Since they receive the Y chromosome from the father, they will not inherit the hemophilia gene. Therefore, all sons will be unaffected. Daughters: They inherit one Xh chromosome from the father (which carries the hemophilia gene) and one X chromosome from the mother. One X chromosome from the father carrying the hemophilia gene (Xh) and one X chromosome from the mother (X).These daughters will be carriers of hemophilia (XhX).

So, the possibility that their child will have hemophilia is 0%, as hemophilia is a recessive disorder and the sons will not inherit the hemophilia gene, while the daughters will be carriers .

Therefore, the correct answer is option 3: 0%.