Britain lost billions of the dollars due to.

Madcow disease

The correct answer is Option (3) - Madcow disease

Britain lost billions of dollars due to "Madcow disease," also known as Bovine Spongiform Encephalopathy (BSE). This disease affected the cattle industry in Britain in the late 20th century, leading to significant economic losses due to the collapse of beef exports, consumer fear, and costs associated with addressing the crisis.