In the following questions a statement of assertion followed by a statement of reason is given. Choose the correct answer out of the following choices.
Assertion : Non-competitive inhibitor inhibits the catalytic activity of enzyme by binding with its active site.
Reason : Non-competitive inhibitor changes the shape of the active site in such a way that substrate can't recognize it. .
Answer & explanation
Correct answer: option 4
Assertion: Non-competitive inhibitors do not bind to the enzyme’s active site. These bind to a different site of enzyme which is called allosteric site.
So, assertion is wrong.
Reason: Non-competitive inhibitors change the shape of the active site of the enzyme in such a way that the substrate will not be able to recognize it.
So, reason is correct.