Select the most appropriate meaning of the given idiom.

Comparing apples with oranges

Unequal comparisons

The most appropriate meaning of the idiom "comparing apples with oranges" is unequal comparisons.

This idiom is used to describe the act of comparing two things that are not alike. It is often used to express the idea that such comparisons are pointless or unfair. For example, you might say "You can't compare apples with oranges. They're two different things." This means that you cannot compare the two things because they are not comparable.

The other options are not as accurate descriptions of the meaning of the idiom.

• Calculation of proteins: This idiom is not related to proteins.
• Comparison between two kinds of fruits: This is a literal description of the idiom, but it does not capture the full meaning.
• To have a health issue: This idiom is not related to health issues.