Practicing Success
In the following compounds, what is the increasing order of their reactivity towards nucleophilic addition reactions? Benzaldehyde, p-Tolualdehyde, p-Nitrobenzaldehyde, Acetophenone |
Benzaldehyde < p-Tolualdehyde < p-Nitrobenzaldehyde < Acetophenone Acetophenone < Benzaldehyde < p-Tolualdehyde < p-Nitrobenzaldehyde Acetophenone < p-Tolualdehyde < Benzaldehyde < p-Nitrobenzaldehyde Benzaldehyde < Acetophenone < p-Tolualdehyde < p-Nitrobenzaldehyde |
Acetophenone < p-Tolualdehyde < Benzaldehyde < p-Nitrobenzaldehyde |
The correct answer is option 3. Acetophenone < p-Tolualdehyde < Benzaldehyde < p-Nitrobenzaldehyde. To determine the increasing order of reactivity towards nucleophilic addition reactions for the given compounds (Benzaldehyde, p-Tolualdehyde, p-Nitrobenzaldehyde, Acetophenone), we need to consider the electronic effects of substituents on the carbonyl group and the nature of the carbonyl compound. Analysis of Each Compound: Benzaldehyde (\(C_6H_5CHO\)): Electronic Effects: The phenyl group slightly stabilizes the carbonyl group through resonance but has a relatively neutral effect overall. Reactivity: It has moderate reactivity towards nucleophilic addition. p-Tolualdehyde (\(p-CH_3C_6H_4CHO\)): Substituent Effect: The methyl group (\(CH_3\)) at the para position is an electron-donating group via the inductive effect and hyperconjugation. Reactivity: The electron-donating effect of the methyl group reduces the electrophilicity of the carbonyl carbon, making it less reactive towards nucleophiles compared to benzaldehyde. p-Nitrobenzaldehyde (\(p-NO_2C_6H_4CHO\)): Substituent Effect: The nitro group (\(NO_2\)) at the para position is a strong electron-withdrawing group through both inductive and resonance effects. Reactivity: The electron-withdrawing effect of the nitro group increases the electrophilicity of the carbonyl carbon, making it more reactive towards nucleophiles compared to benzaldehyde. Acetophenone (\(C_6H_5COCH_3\)): Nature of Carbonyl Group: As a ketone, the carbonyl carbon in acetophenone is less electrophilic compared to aldehydes because of the electron-donating effect of the alkyl group (\(CH_3\)). Reactivity: Ketones are generally less reactive towards nucleophilic addition than aldehydes due to steric and electronic factors. Increasing Order of Reactivity: Combining these considerations, the order of reactivity towards nucleophilic addition reactions is: Acetophenone: Least reactive because it is a ketone and the carbonyl carbon is less electrophilic. p-Tolualdehyde: Less reactive than benzaldehyde due to the electron-donating effect of the methyl group. Benzaldehyde: More reactive than p-tolualdehyde and acetophenone. p-Nitrobenzaldehyde: Most reactive due to the strong electron-withdrawing effect of the nitro group. |