The word "refute" means to prove a statement or argument to be false or incorrect. To find the best antonym (opposite) for "refute," we should look for a word that means to support or accept a statement or argument as true.

Option 1: "Disprove" is a synonym of "refute" and, therefore, not the opposite.

Option 2: "Subscribe" means to express agreement or support, which makes it a suitable antonym for "refute."

Option 3: "Recommend" means to suggest or endorse something, which is not the opposite of "refute."

Option 4: "Rebut" means to counter or provide evidence against an argument, which is similar in meaning to "refute" and is not the opposite.

The best antonym for "refute" among the given options is Option 2: "Subscribe."