Match List-I with List-II:

Choose the correct answer from the options given below:

(A)-(III), (B) - (IV), (C) - (I), (D)-(II)

The correct answer is Option (1) - (A)-(III), (B) - (IV), (C) - (I), (D)-(II)

α-I antitrypsin - This is a protease inhibitor and its deficiency leads to emphysema due to the degradation of the lung tissue. Therefore, α-I antitrypsin corresponds to Emphysema.

Cry IAc - This is also a protein from Bacillus thuringiensis and is notably effective against Cotton Bollworm.

Cry IAb - Part of a family of proteins from Bacillus thuringiensis used as a biological pesticide. Cry IAb is notably effective against certain types of Lepidoptera, including the European Corn Borer .

A nematode Meloidegyne incognitia infects the roots of tobacco plants and causes a great reduction in yield. A novel strategy was adopted to prevent this infestation which was based on the process of RNA interference (RNAi).Using Agrobacterium vectors, nematode-specific genes were introduced into the host plant . The introduction of DNA was such that it produced both sense and anti-sense RNA in the host cells. These two RNA’s being complementary to each other formed a double stranded (dsRNA) that initiated RNAi and thus, silenced the specific mRNA of the nematode.