The correct answer is Option (2) → cis-platin
- Cis-platin (cis-diamminedichloroplatinum(II)) is a well-known platinum-based chemotherapeutic agent widely used in cancer treatment. It acts as an alkylating-like agent, forming DNA cross-links that inhibit DNA replication and transcription, effectively stopping the growth of tumour cells. It is particularly effective against testicular, ovarian, bladder, and lung cancers.
Why not the others?
- D-penicillamine: A chelating agent primarily used for Wilson's disease (copper overload) and rheumatoid arthritis; no significant anti-tumour activity.
- EDTA: A general chelating agent for heavy metal poisoning; not used as an anti-cancer drug.
- Desferrioxamine B (desferrioxamine): An iron chelator used for iron overload conditions (e.g., thalassemia); it has no established role in inhibiting tumour growth clinically.
Thus, the correct answer is cis-platin. |
