Practicing Success

Target Exam

CUET

Subject

Biology

Chapter

Biotechnology and its Applications

Question:

Read the given passage and answer he questions that follow :-

Previously, to treat diabetes, insulin was extracted from the pancreas of slaughtered cattle and pigs. However, this animal-derived insulin sometimes led to allergic reactions or other adverse responses in certain patients due to the presence of foreign proteins. Human insulin, on the other hand, is composed of two short polypeptide chains (chain A and chain B) that are connected by disulfide bridges. In mammals, including humans, insulin is initially produced as a pro-hormone, which contains an additional segment known as the C-peptide. This C-peptide is absent in the final mature form of insulin, as it is removed during the process of insulin maturation.

Why is the fermenter important for the production of human insulin by transgenic bacteria?

Options:

It provides optimal conditions for the transgenic to multiply rapidly.

It facilitates the extraction and purification of insulin from transgenic bacteria.

It maximizes the rate of fermentation of transgenic bacteria.

It provides the low-oxygen conditions that are important for insulin production.

Correct Answer:

It provides optimal conditions for the transgenic to multiply rapidly.

Explanation:

To create large amounts of the cells, the genetically modified bacteria or yeast are grown in large fermentation vessels that contain all the nutrients they need. The more the cells divide, the more insulin is produced. The bacterial cell is placed in a fermenter to allow reproduction under perfect conditions (warmth, moisture and oxygen).