Fill in the blanks with the most appropriate option:-

Jenifer is quite satisfied ……… her new job.

with

The correct option to fill in the blank is with.

The sentence is about Jenifer's satisfaction with her new job. The word "with" is used to indicate that Jenifer is happy and content with her new job.

The other options are not as appropriate:

• To is used to indicate movement towards something. In this sentence, it would not be accurate to use "to", as Jenifer is not moving towards her new job.
• From is used to indicate movement away from something. In this sentence, it would not be accurate to use "from", as Jenifer is not moving away from her new job.
• By is used to indicate the means by which something is done. In this sentence, it would not be accurate to use "by", as Jenifer's satisfaction is not caused by her new job.