Match the Column 1 with Column 2 :
| Column 1 | Column 1 |
| (a) Down's Syndrome | (i) Mendelian Disease |
| (b) Turner's Syndrome | (ii) Trisomy 21 |
| (c) Klinefelter's Syndrome | (iii) Karyotype of 47, XXY |
| (d) Thalassemia | (iv) 45 with XO |
Answer & explanation
Correct answer: option 1
The correct answer is Option (1)- a-ii; b-iv; c-iii; d-i
| Column 1 | Column 1 |
| (a) Down's Syndrome | (ii) Trisomy 21 |
| (b) Turner's Syndrome | (iv) 45 with XO |
| (c) Klinefelter's Syndrome | (iii) Karyotype of 47, XXY |
| (d) Thalassemia | (i) Mendelian Disease |
(a) Down's Syndrome - (ii) Trisomy 21 : Down's Syndrome is a genetic disorder characterized by the presence of an extra copy of chromosome 21, resulting in a total of three copies (trisomy) of this chromosome.
(b) Turner's Syndrome - (iv) 45 with XO : Turner's Syndrome occurs due to a chromosomal abnormality where a female is born with only one X chromosome (45,XO).
(c) Klinefelter's Syndrome - (iii) Karyotype of 47 ,XXY : Klinefelter's Syndrome is characterized by the presence of an extra X chromosome in males, resulting in a karyotype of 47,XXY.
(d) Thalassemia - (i) Mendelian Disease : Thalassemia refers to a group of inherited blood disorders caused by mutations in the genes that produce hemoglobin and is considered a Mendelian genetic disorder due to its inheritance patterns.