What is the name of the reaction when acetamide is converted to methylamine?
Answer & explanation
Correct answer: option 3
The correct answer is Option (3) → Hoffmann Bromamide degradation reaction
- Hofmann Bromamide Degradation is used to convert a primary amide (R–CONH₂) into a primary amine (R–NH₂) with one carbon less.
- In this reaction, acetamide (CH₃CONH₂) reacts with Br₂ and NaOH to give methylamine (CH₃NH₂):
$CH_3CONH_2+Br_2+4NaOH→CH_3NH_2+Na_2CO_3+2NaBr+2H_2O$
Hence, the correct reaction is Hofmann Bromamide degradation reaction.