The most appropriate option to fill in the blanks is destiny.
The sentence "Man is the maker of his own destiny" means that man is responsible for his own future. The other options are not as appropriate.
- Destination means the place where someone is going or intends to go. This does not make sense in the context of the sentence, as man is not simply going to a place, but he is creating his own future.
- Decides means to make a decision about something. This does not make sense in the context of the sentence, as man is not simply making a decision, but he is creating his own future.
- Destine means to decide or determine the future of someone or something. This is the most appropriate word to use in the sentence, as it accurately reflects the fact that man is responsible for his own future.
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