Which system in the human body is primarily attacked by the adults of Wuchereria bancrofti?

Lymphatic system

Wuchereria bancrofti and Wuchereria malayi are types of filarial worms that can cause a condition known as elephantiasis or filariasis. These worms live in the lymphatic vessels of the lower limbs, as well as in the genital organs, leading to chronic inflammation and damage over many years.The adult worms reside in the lymphatic vessels, which are a part of the lymphatic system. They can cause obstruction and damage to these vessels, leading to the accumulation of lymph fluid in various parts of the body, particularly the limbs and genital area.

The transmission of these pathogens occurs through the bite of female mosquito vectors. Female mosquitoes of certain species, such as the Culex, Aedes, and Anopheles mosquitoes, serve as the intermediate hosts for the filarial worms. When a mosquito feeds on the blood of an infected individual, it ingests microscopic larvae called microfilariae, which circulate in the bloodstream.

Inside the mosquito's body, the microfilariae undergo further development and transform into infective larvae. These larvae migrate to the mosquito's salivary glands and can be transmitted to a healthy person when the mosquito bites again. During the feeding process, the infective larvae are deposited onto the person's skin, where they can enter the bloodstream through the mosquito's bite wound.

Once inside the human body, the infective larvae migrate to the lymphatic vessels and mature into adult worms. These adult worms can live for many years, causing chronic inflammation and obstruction in the affected lymphatic vessels. This leads to the accumulation of lymph fluid, swelling, and ultimately the characteristic enlargement and deformities seen in elephantiasis.

It is important to note that the transmission of Wuchereria is specific to the bite of infected female mosquitoes. Taking measures to prevent mosquito bites, such as using mosquito nets, wearing protective clothing, and using insect repellents, can help reduce the risk of acquiring filarial infections like elephantiasis. Additionally, public health efforts often involve mosquito control strategies to reduce the mosquito population and prevent the spread of these diseases.