Statement I :Transformation of normal cells into cancerous neoplastic cells may be induced by physical, chemical or biological agents.
Statement II : Ionising radiations like X-rays and gamma rays and non-ionizing radiations like UV cause DNA damage leading to neoplastic transformation.

Both statement I and statement are correct.

The correct answer is Option (3) – Both statement I and statement are correct.

Statement I: The transformation of normal cells into cancerous neoplastic cells can indeed be induced by various factors, including physical (such as radiation), chemical (such as carcinogens). These agents can cause genetic mutations or alterations in cellular processes that lead to uncontrolled cell growth and the development of cancer.

Statement II: Both ionizing radiations like X-rays and gamma rays and non-ionizing radiations like UV (ultraviolet) rays can cause DNA damage, which can lead to neoplastic transformation. Ionizing radiation directly damages DNA by causing breaks in the DNA strands or altering the nucleotide sequence, while UV radiation induces DNA damage mainly through the formation of thymine dimers, which can result in mutations and ultimately contribute to the development of cancer.

So, transformation of normal cells into cancerous neoplastic cells may be induced by physical, chemical or biological agents. These agents are called carcinogens. Ionising radiations like X-rays and gamma rays and non-ionizing radiations like UV cause DNA damage leading to neoplastic transformation.