The construction of the first recombinant DNA molecule involved linking a gene encoding antibiotic resistance with a native plasmid of which organism?

Salmonella typhimurium

a) Salmonella typhimurium

The construction of the first recombinant DNA molecule involved linking a gene encoding antibiotic resistance with a native plasmid of Salmonella typhimurium.

Stanley Cohen and Herbert Boyer accomplished this in 1972 by isolating the antibiotic resistance gene from a plasmid responsible for conferring antibiotic resistance in Salmonella typhimurium. The plasmid DNA acted as a vector to transfer the antibiotic resistance gene to other organisms.