The construction of the first recombinant DNA molecule involved linking a gene encoding antibiotic resistance with a native plasmid of which organism?

Salmonella typhimurium

The correct answer is Option (1) –Salmonella typhimurium

The construction of the first recombinant DNA emerged from the possibility of linking a gene encoding antibiotic resistance with a native plasmid (autonomously replicating circular extra-chromosomal DNA) of Salmonella typhimurium. Stanley Cohen and Herbert Boyer accomplished this in 1972 by isolating the antibiotic resistance gene by cutting out a piece of DNA from a plasmid which was responsible for conferring antibiotic resistance.

In genetic engineering, a vector is a DNA molecule used to carry and transfer foreign DNA into a host cell. Plasmids are one of the common types of vectors used in genetic engineering experiments. They are small, circular DNA molecules that exist naturally in bacterial cells and can replicate independently of the chromosomal DNA.