Practicing Success

Target Exam

CUET

Subject

Chemistry

Chapter

Organic: Chemistry in Everyday Life

Question:

Which of the following is likely to cause an ulcer in the stomach?

Options:

Luminal

Aspirin

Phenelzine

Iproniazid

Correct Answer:

Aspirin

Explanation:

The correct answer is option 2. Aspirin.

Among the options provided, aspirin is likely to cause ulcers in the stomach.

(2) Aspirin:
Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the activity of the enzyme cyclooxygenase (COX). While it is effective in reducing pain and inflammation, it can also interfere with the protective mechanisms of the stomach lining. Aspirin can inhibit the synthesis of prostaglandins, which play a role in maintaining the integrity of the stomach lining and regulating gastric acid secretion. As a result, prolonged or high-dose use of aspirin can lead to irritation of the stomach lining, potentially causing gastric ulcers.

The other options:

(1) Luminal:
"Luminal" is a term that generally refers to substances related to the lumen of a hollow organ, such as the gastrointestinal tract. It does not specify a particular substance that can cause ulcers.

(3) Phenelzine:
Phenelzine is a monoamine oxidase inhibitor (MAOI) used as an antidepressant. While it may have side effects, it is not commonly associated with causing ulcers in the stomach.

(4) Iproniazid:
Iproniazid is a monoamine oxidase inhibitor that was historically used as an antidepressant. Like phenelzine, it is not typically associated with causing ulcers in the stomach.

In summary, aspirin is known to have the potential to cause stomach ulcers due to its impact on prostaglandin synthesis and the protective mechanisms of the stomach lining.