Read the paragraph given below and answer the question.
If a person is born with a hereditary disease, can a corrective therapy be taken for such a disease? Gene therapy is an attempt to do this. Gene therapy is a collection of methods that allows correction of a gene defect that has been diagnosed in a child/embryo. Here genes are inserted into a person's cells and tissues to treat disease.
Gene therapy method involves:
Answer & explanation
Correct answer: option 2
The correct answer is Option (2) → Delivery of normal functional gene in the embryo to compensate for non functional gene
Option (1) Cloning of cells with alternative gene — Incorrect. Cloning of cells is not the method; a normal gene is delivered.
Option (2) Delivery of normal functional gene in the embryo to compensate for non functional gene — Correct. A normal functional gene is delivered to compensate for the non-functional gene.
Option (3) Modification of defective genes in the cells — Incorrect. The defective gene is not modified; a normal copy is added.
Option (4) cDNA recombination — Incorrect. cDNA of ADA is used in the treatment, but the method is the delivery of a normal gene.
Note: The passage is taken from NCERT. NTA has put lines of the NCERT text together to make it. Most CUET (UG) questions come straight from NCERT, so study the book line by line, including figures and their titles.
NCERT Extract:
Gene Therapy – “If a person is born with a hereditary disease, can a corrective therapy be taken for such a disease? Gene therapy is an attempt to do this. Gene therapy is a collection of methods that allows correction of a gene defect that has been diagnosed in a child/embryo. Here genes are inserted into a person’s cells and tissues to treat a disease. Correction of a genetic defect involves delivery of a normal gene into the individual or embryo to take over the function of and compensate for the non-functional gene.”