What is the product when p-Nitrophenol is reduced with Sn+HCl followed by reaction with Ac2O?
Answer & explanation
Correct answer: option 2
The correct answer is option 2. Paracetamol.
The product formed when p-Nitrophenol is reduced with \(Sn + HCl\) followed by reaction with \(Ac_2O\) is Paracetamol.
Here is a breakdown of the reaction sequence:
Reduction: \(Sn + HCl\) acts as a reducing agent, converting the nitro group (-NO₂) in p-Nitrophenol to an amino group (-NH₂). This reaction generates p-Aminophenol.
Acetylation: \(Ac_2O\) (acetic anhydride) reacts with the amino group (-NH₂) in p-Aminophenol. The acetyl group (CH₃CO-) from \(Ac_2O\) replaces a hydrogen atom on the nitrogen, forming an amide bond (C-N) and producing Paracetamol.
Therefore, the final product is Paracetamol, a pain reliever and fever reducer commonly known by the brand name Tylenol.
