The correct answer is Option (1) → Phosphodiester linkage
Explanation:
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In nucleic acids (DNA and RNA), nucleotides are linked together by phosphodiester bonds.
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This linkage occurs between the 3′ hydroxyl group of one sugar (deoxyribose or ribose) and the 5′ phosphate group of the next nucleotide.
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It forms a strong covalent bond, creating the sugar-phosphate backbone of nucleic acids.
Incorrect options:
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Phosphate linkage: A vague term, not specific to the bond between nucleotides.
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α-linkage and β-linkage: Refer to glycosidic bonds in carbohydrates, not nucleotides.
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