Ribonuclease make cuts in

The correct answer is Option (1) → RNA

Option (1) RNA — Correct. Each enzyme acts on its own kind of molecule. Ribonuclease breaks RNA; deoxyribonuclease breaks DNA, and protease breaks proteins. This is why ribonuclease is used to remove RNA while isolating DNA.

NCERT Extract:
Isolation of the Genetic Material (DNA) – “… Since the DNA is enclosed within the membranes, we have to break the cell open to release DNA along with other macromolecules such as RNA, proteins, polysaccharides and also lipids. This can be achieved by treating the bacterial cells/plant or animal tissue with enzymes such as lysozyme (bacteria), cellulase (plant cells), chitinase (fungus). You know that genes are located on long molecules of DNA interwined with proteins such as histones. The RNA can be removed by treatment with ribonuclease whereas proteins can be removed by treatment with protease.”