Arrange the given statements in correct sequence of their occurrence in replication of retrovirus.
A. Viral DNA incorporates into host genome
B. Virus infects normal cell
C. Viral DNA is produced by reverse transcriptase
D. New viral RNA is produced by the infected cell
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 2
The correct answer is Option (2) → B, C, A, D
B. Virus infects normal cell — first. The retrovirus (such as HIV) enters the host cell with its RNA genome.
C. Viral DNA is produced by reverse transcriptase — second. The enzyme copies the viral RNA into DNA.
A. Viral DNA incorporates into host genome — third. The viral DNA joins the DNA of the host cell.
D. New viral RNA is produced by the infected cell — last. The host cell now reads the viral genes and makes new viral RNA and new virus particles.
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NCERT Extract:
AIDS – “… After getting into the body of the person, the virus enters into macrophages where RNA genome of the virus replicates to form viral DNA with the help of the enzyme reverse transcriptase. This viral DNA gets incorporated into host cell’s DNA and directs the infected cells to produce virus particles (Figure 7.6).”