Match the Column I with Column II .

1-D, 2-C , 3-B ,4- A

The correct answer is Option (3)- 1-D, 2-C , 3-B ,4- A

1. Streptokinase, produced by the bacterium Streptococcus and genetically modified, serves as a "clot buster" in the removal of blood clots from the vessels of individuals who have experienced a heart attack.

2. Aspergillus niger is a fungus known for its ability to produce citric acid. It is widely used in the food and beverage industry for the production of citric acid, which is commonly used as a flavoring agent and preservative.

3. Baculoviruses are a group of viruses that infect insects, particularly caterpillars. One type of baculovirus is the nucleopolyhedrovirus, which is used as a biocontrol agent to control pest insects. Nucleopolyhedroviruses are specific to certain insect species and are considered safe for non-target organisms.

4. Penicillin was isolated from the mould Penicillium notatum. The discovery of penicillin is credited to Sir Alexander Fleming, a Scottish biologist, who noticed its properties accidentally in 1928. While studying Staphylococcus bacteria, he observed that a mould contaminating his bacterial culture inhibited the growth of the bacteria. Upon closer examination, he identified the mould as Penicillium notatum.