ASSERTION: ADA deficiency can not be cured permanently in adults.
REASON: The genetically engineered lymphocytes survive only for a limited time in body.
REASON: The genetically engineered lymphocytes survive only for a limited time in body.
Answer & explanation
Correct answer: option 1
The genetically engineered lymphocytes are not immortal and survive only for a limited time in body.. Gene therapy at an adult stage requires periodic infusion of genetically engineered lymphocytes. However, if the gene therapy is done at early embryonic stages, it could be a permanent cure.